Innovations in Spinal Hemangioblastoma Management
Published: 2020-07-18
Page: 137-149
Issue: 2020 - Volume 3 [Issue 1]
Akul Munjal *
Department of Orthopedics, Medical College of Georgia, Georgia.
Vamsi Reddy
Department of Neurosurgery, Medical College of Georgia, Georgia.
Kashif Malik
Department of Anesthesia, Medical College of Georgia, Georgia.
Ananya Munjal
Department of Surgery, Medical College of Georgia, Georgia.
Uzondu Agochukwu
Department of Orthopedics, Medical College of Georgia, Georgia.
Kelly Homlar
Department of Orthopedics, Medical College of Georgia, Georgia.
*Author to whom correspondence should be addressed.
Abstract
Introduction: Spinal hemangioblastomas are benign, rare neoplasms of spinal cord vasculature. They may occur as solitary lesions or with associated intracranial hemangioblastomas, this association is seen in Von Hippel Lindau syndrome (VHL).
Aims: This literature review serves to highlight various innovative therapeutic modalities used to treat this pathology.
Methods: The articles were obtained though PubMed Central or Google scholar, initially more than 30 articles were selected; however, additional only: clinical trials, retrospective studies, or case series/ reports were selected. This resulted in final analysis of 20 articles.
Results: Surgical resection is carried out with either an: open or microsurgical approach with either an endoscopic or minimally invasive technique. The specific surgical intervention depends on the spread of the neoplasm. Pre-operative angiography is a critical predictor of surgical success. Arterial embolization may also be conducted preoperatively to minimize neoplasm vascularity. Stereotactic radiosurgery often conducted with gamma knife or LINAC, has remarkably improved treatment. Pharmacologic therapies.
Keywords: Spine, hemangioblastoma, oncology, orthopedics-oncology, Von-Hippel Lindau.