Asian Journal of Orthopaedic Research <p style="text-align: justify;"><strong>Asian Journal of Orthopaedic Research</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/AJORR/general-guideline-for-authors">Click here for Types of paper</a>) on all aspects of&nbsp;Orthopaedic&nbsp;research. By not excluding papers based on novelty, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer-reviewed, open-access INTERNATIONAL journal.</p> en-US (Asian Journal of Orthopaedic Research) (Asian Journal of Orthopaedic Research) Tue, 20 Dec 2022 11:33:33 +0000 OJS 60 Molecular Detection of Bone Sialoprotein-Binding Protein (bbp) Genes among Clinical Isolates of Methicillin Resistant Staphylococcus aureus from Hospitalized Orthopedic Wound Patients <p><strong>Background and Objectives: </strong>Methicillin Resistant<em> Staphylococcus</em> <em>aureus</em> (MRSA) is one of the bacteria that are frequently encountered in orthopedic practice causing human skeletal infections due to expression of Genes encoding Microbial Surface Components Recognizing Adhesive Matrix Molecules that aid in microbial invasion of bone. As such, this study was aimed at screening for Bone sialoprotein-binding protein (<em>bbp</em>) Genes among Clinical Isolates of Methicillin Resistant <em>Staphylococcus</em> <em>aureus </em>from Hospitalized Orthopedic Wound Patients.</p> <p><strong>Methodology: </strong>Aseptically, four hundred (400) fracture and post-surgical wound swab samples were collected from orthopedic wound patients and subjected to standard microbiological protocol for isolation and identification of MRSA using Brilliance MRSA II Agar and Double Disc Diffusion Test with inclusion Oxacillin (5μg) and Cefoxitin (30μg). Randomly selected MRSA strains were further screen for Penicillin binding protein 2a (<em>mecA</em>) and Bone sialoprotein-binding protein (<em>bbp</em>) gene by PCR using specific primer.</p> <p><strong>Results: </strong>MRSA had an overall detection rate of 164 (41.0%), with an increase prevalence rate of 86 (21.5%) in post-surgical wound samples, followed by fracture wound samples (78 (19.5%). However, the isolation rate of MRSA was significantly associated with the sample source <em>p </em>value &lt;0.05. Of the ten (10) selected MRSA strain<em>, mecA</em> gene was genetically detected 100 % comprising of 50.0% from postsurgical wound patient (MR1-5) and 50.0% from fracture wound patient (MR6-10) while the bone sialoprotein-binding protein (<em>bbp</em>) gene was identified in 100% of MRSA strain from both post-surgical wound (MR1-5) and fracture wound (MR6-10) patients each accounted for 50.0% of the total amplified gene.</p> <p><strong>Conclusion: </strong>This study report <em>MecA</em> and <em>bbp</em> expression in hospitalized orthopedic wound patients, emphasizing that <em>mecA</em> and <em>bbp</em> detection can be used as a marker of MRSA bone invasion, especially in orthopedic wound infections. To reduce the risk of infection and to halt the clonal proliferation of these virulent strains, a proper wound care/hygiene, comprehensive and ongoing surveillance system that provides epidemiological and genetic information is required.</p> Ikemesit Udeme Peter, Nwankwo Chinenye Emelda, Ezinwanne Blessing Chukwu, Justina Nnenna Ngwu, Henrietta Onyinye Uzoeto, Ezeh Chinonyelum Moneth, Aduaka Oluchukwu Stella, Christiana Inuaesiet Edemekong, Ekuma Perpetua Uzoamaka, Agabus Chidiebube Nwuzo, Ifeanyichukwu Romanus Iroha ##submission.copyrightStatement## Tue, 20 Dec 2022 00:00:00 +0000 Non-wedge Technique for Valgus Subtrochanteric Osteotomy in Pediatric Femoral Neck Non-union <p><strong>Aims:</strong> The aim of this retrospective study was to evaluate the clinical and radiological outcomes of using valgus subtrochanteric osteotomy in pediatric femoral neck non-union in terms of Ratliff functional score and time to union respectively.</p> <p><strong>Study Design: </strong>Case Series.</p> <p><strong>Place and Duration of Study: </strong>Ghurki Trust Teaching Hospital Lahore Pakistan. Study conducted between Jan 2016 to Dec 2019.</p> <p><strong>Methodology: </strong>This was a retrospective study of 5 children with femoral neck non-union who underwent osteosynthesis and valgus subtrochanteric osteotomy at Ghurki Trust Teaching hospital between 2016 and 2019. Clinico-demographic profile of patients and functional and radiological outcomes in terms of Ratliff grading and time to union respectively are reported. All patients had a minimum of 2 years followup.</p> <p><strong>Results: </strong>This study included five patients (two males and three females with mean age of 9.8 ± 1.92 years). All patients achieved fracture union, seen within an average of 18 ±6.37 weeks and of the osteotomy site within 13 ± 2.9 weeks. Neck shaft angle improved from average 107 degrees (range 100-110) preoperatively to 137 degrees postoperatively (range 130-140). Pre-operative radiologic signs of AVN was shown in all patients which disappeared completely in 4 patients. Mean limb-length discrepancy decreased from 2.9 cm preoperatively to 0.8 ± 0.57cm post-operatively. According to Ratliff criteria, 4patients had good whereas one patient had fair functional outcome. There were no intra-operative or early post-operative complications recorded in our series.</p> <p><strong>Conclusion: </strong>We report that valgus subtrochanteric osteotomy in non-united femoral neck fractures in children is cost-ef­fective and technically less demanding procedure and is associated with good clinical and radiological outcomes.</p> Saeed Ahmad, Irfan Qadir, Jahanzeb Mazari, Amer Aziz ##submission.copyrightStatement## Tue, 20 Dec 2022 00:00:00 +0000 Outcomes of Osteonecrosis of Femur Head by Core Decompression and Tensor Fascia Lata Based Muscle Pedicle Bone Graft <p><strong>Purpose:</strong> Osteonecrosis of femoral head (ONFH) is the major cause of musculoskeletal disability. Core decompression (CD) is the most widely used strategy for the management of ONFH but it lacks the ability to increase the vascularization around the necrotic femoral head. So the purpose of the study was to evaluate the outcome of CD with tensor fascia lata muscle pedicle bone graft in ONFH patients.</p> <p><strong>Methods:</strong> This prospective study was conducted on 26 ONFH patients. Core decompression with TFL muscle pedicle grafting methods was used in all the patients. The outcome of the technique was evaluated using Harris hip score.</p> <p><strong>Results:</strong> In this study, the major risk factor ONFH was alcohol intake followed by chronic steroid use. Majority of the patients (57.69%) were in stage III ONFH. The Harris Hip Score was excellent in 14 hips (53.846%), fair in 2 hips (7.692%) and poor in 1 hip (3.84%) respectively. There was a significant increase in post operative Harris hip score as compared to preoperative (86.6 ± 8.0 vs 63.7 ± 6.7).</p> <p><strong>Conclusion: </strong>Tensor fascia lata muscle pedicle grafting along with core decompression is a reliable technique for pain reduction and improved vascularization in necrotic femoral head.</p> Sameer Tyagi, Rajiv V. Kulkarni, Buddhadeb Nayak, Anupam Inamdar ##submission.copyrightStatement## Tue, 27 Dec 2022 00:00:00 +0000 Anatomical and Surgical Basis for the Treatment of Paralytic Knees <p>This review is to highlight the anatomical and surgical basis for the treatment of paralytic knees that lead to a grave functional handicap because of its intermediate situation in lower limb.</p> <p>&nbsp;Paralytic knee disease affects muscular balance and osteoarticular growth to the point of sometimes compromising the possibility of standing and walking.</p> <p>Combined with a good knowledge of the main etiologies (Poliomyelitis, myelomeningocele and cerebral palsy), it enables the bases of the orthopedic treatment to be defined. Consequences related to paralytic knee desease may lead to neuroorthopaedic deformities in the joints.</p> <p>Orthopaedic surgical treatment of the consequences of knee paralysis is varied both in terms of the diversity of the surgical techniques that can be carried out (tenotomies, lengthenings, transfers, osteotomies...) and the patient’s profile. It must essentially meet functional and not morphological.</p> C. Elkassimi, S. Rouadi, M. Fadili, E. Bachkira, A. M. Abdullah, I. Jadib, O. Hadad, K. Tabbak, M. A. Kharoub, A. Rafaoui, A. Messoudi, M. Rahmi, M. Rafai ##submission.copyrightStatement## Sat, 24 Dec 2022 00:00:00 +0000